http://www.smartgroups.com/message/readmessage.cfm?
gid=1423922&messageid=6781&startid=6783
 
Enlarged spleens are common in ferrets.  Most of the time it is just
the spleen making red blood cells (extra medullary hematopoiesis) or
responding to an immune stimuli (Helicobacter, AD, or bacteria).  It
can also be enlarged from cancer (Lymphoma) or from hypersplenism.  If
it gets big enough then remove it.  The spleen is part of the immune
system, so do not remove it unless it is necessary.
 
Hope that helps,
Jerry Murray, DVM
[Posted in FML issue 4347]