I have been vaccinating my ferrets (shelter and personal) at home since 1996. I use primarily Fervac-D, but have vaccinated using Galaxy-D with ferrets that have had previous reactions to Fervac. So far, none (of course, its only 4) of the ferrets that reacted to Fervac have also reacted to Galaxy..but I digress. I premedicate my ferrets with pediatric benadryl 30 minutes prior to vaccinating. I only vaccinate when I have at least 1 hour of open vet time after the time of vaccination. I also have arrangements with both my regular vet and an 'emergency vet' (this vets office is located 2 blocks from my house and is somewhat ferret friendly, just not as experienced as my regular vet). If my ferrets begin to react (Oh, did I say that before I give the shots, I am ready to walk out the door, including having a carrier ready?) I make the decision which vet I am going to as I walk out the door, based on the severity of symptoms. I can't stress enough to anyone that is considering to vaccinate at home, that you be as prepared as possible. I have seen a couple ferrets that the reaction was so mild (just a little redness and swelling at the site of injection) to a full-blown anaphylactic shock in which the ferret almost died. Certainly keeps those high-speed driving skills current. Personal opinion here - if you have a ferret react to Fervac, consider using Galaxy. It is an off-label use canine distemper vaccine and while not tested for effectiveness in ferrets, I believe that it does provide protection. It certainly provides more than not vaccinating the animal again, and thats usually the only other choice. I would *never* vaccinate a ferret that has had a previous reaction to the vaccine. If you do buy your vaccines, I would also recommend using the overnight shipment delivery, if possible. Keeping them cold is a good thing. Depending on your state (IIRC, some prohibit the shipment of syringes) purchasing needles/syringes may be difficult. Virginia, so far, doesn't seem to care. HTH Lisa, Head Ferret The Ferret Haven "By-the-Sea" URL: http: www.kozykingdom.com/ferrethaven Want to help The Ferret Haven By-the-Sea? Register at iGive.com by cutting and pasting this link: http://www.iGive.com/html/ssi.cfm?CID=1236&MID=854 [Posted in FML issue 2836]