This is the first part of the post that did not get posted to the FML yesterday, but I am re-posting both parts today. This post is rather graphic, so if you have a weak stomach, you may want to pass on it. We need information from anyone else in the ferret community that has seen or dealt with this parasite. I am posting this to the FML, the shelter list, and several individuals, since it is time sensitive. I know they are busy, and may be a little behind on the FML, as I am. Thanks... In April, a one year old sable gib was turned over to our shelter by the local humane society. Tigger has a delightful personality, and gets along with any ferret you put him with. He has a family waiting for him, as soon as they are moved, and we correct a 'health' problem. When Tigger came in, he had a raised, solid, blister- like mass, a little smaller than a dime, on the top of his left front foot. I took him to my vet, but he did not seem too concerned, but decided to we should watch it for a while. It did get larger, and mid-May he developed a 'mass' higher on this same leg, so Tigger went back to the Dr. again. The new mass appeared to be an infection, so Tigger was put on Clavamox. The new mass went down, but there still feels like some scar tissue, or something of the sort, in the tissues at this site. The antibiotic did not affect the mass on his foot, and by this time, it was as large in diameter as a nickle, and raised not quite a half an inch in height. Dr. Higgins, at this point (5/24) did a needle aspirate, and sent the sample to a lab in Columbus. The information that came back on the lab report is as follows: HISTOPATHOLOGIC or CYTOLOGIC DIAGNOSIS Needle Aspirate: Foot: Severe parasitism and eosinophilic granulomatous inflamation Large numbers of larvae with annulated cuticle and very long thin tail are present. Uterine eggs, as yet undeveloped, are also present. The Larvae do not stain, and sometimes have basophilic large granules in their bodies. BIOLOGICAL BEHAVIOR/COMMENTS The identy of the larvae is uncertain. I'ld need an adult to try to classify the parasite. There are multiple possibilities of worms which could cause a subcutaneous/muscle lesion or obstruct lymphatics. Suspect spirurid or rhabditiform larvae. (end) Dr. Higgins has never seen anything like this before, and, needless to say, we were both rather shocked. Ferrets Rabbits and Rodents does not mention this particular infestation, however, does mention other subdermal cysts, and recommends removing the worm, debriding the wound, and taking appropriate measures to prevent infection. Fox, Biology and Disease of the Ferret, (Pages 540 through 545) does mention a worm which...'is a spirurid nematode'... causing a disease known as Dracunculiasis. In this disease, simply put, a worm lives inside a dermal blister, up to 12 months or longer, until mature. At this point, when the blister comes into contact with fresh water, the blister ruptures, and the worm emerges. The female worm then ruptures, and releases ... 'tens of thousands of motile first-stage larvae'... Unfortunately, Fox doesn't give any treatment for eradicating the parasite. This is a natural parasite of raccoons, weasels, and other carnivores in North America. I was out of town yesterday when Dr. Higgins called. I believe he had been in contact with the lab again. Appearently they feel that this is probably what the infestation is. [Posted in FML issue 2695]