Celeste, my Gus had diarrhea like yours for two weeks after I first got him. I kntroduced him to a home with one other ferret. He was neglected pretty bad and did not know what another ferret was. So, Hershey would go to say hi and Gus would be so scared, he would defecate. Needless to say, his diarrhea never improved. I was an arrogant idiot and just kept saying that it was stress related and it would eventually improve. this went on for 2 weeks. Eventually , within 36 hours, he stopped eating and became seriously dehydrated and lethargic. Well, finally got the heads up and rushed him to the emergency room for sub-Q fluids. the next day, we were at the vet as soon as the doors opened. Diagnosis, ECE... Now, the point of me telling that story is that after almost a week of sub-Q fluids, meds and forced feedings, he is stable, but still has very bad diarrhea. Doctor seems to think that the prolonged episode of diarrhea has inflammed his intestinal lining and he has the equivalent of chrone's disease (a human disease). It could be that your ferret has the same secondary problem. Since this is more likely that worms, I would reccommend trying the prednisone first. My vet told me to give him till Monday, then start him on pred because that was the likely reason he wasn't improving. Good luck, and I hope my story helps. Paige [Posted in FML issue 2692]