Q:"Why do you (and others) advise that ferrets not be fed garlic? [or onion]" A: Its hard to get them to eat after-dinner mints and their breath is horrible. And the belching and gas.... Both onion and garlic belong to the same group of plants, and are generally refered to together as allium. Several animals have shown toxic effects when fed high amounts of allium, including cattle, sheep, horses, and dogs. Some evidence suggests cats and ferrets are also in danger. The problem is a volatile oil called n-propyl disulphide (a strong irritant; makes you cry). The ingestion of this compound causes Heinz bodies inside red blood cells. These red blood cells are then removed by the body at a higher rate than normal, causing anemia. Symptoms include a loss of desire to eat, tachycardia, staggering, jaundice, haemoglobinuria, collapse and occasional death; all signs of basic anemia. It is important to note that the problems only occur in instances where the diet is constant and heavy with allium. There is no evidence the occasional ingestion of the oil causes any long-term problems, and several studies show the opposite; small amounts of the compound may increase the ability of the immune system to fight viral infections. I might point out that neither the good nor bad effects have been *proven* with *ferrets*, are far as I can tell from the available literature. I think the real danger is not with healthy animals, but with it's use in duck soup and other foods designed to promote the health of ill or dying ferrets. These animals are already stressed, and allium compounds may cause unforseen problems. This may be a hypothetical argument, but why take the risk with sick or debilitated ferrets? Personally, the occasional injestion by healthy ferrets would not worry me. I have found, however, that some people simply don't read or understand things told them, so while I privately say it isn't much of a problem if occassionaly fed in small amounts to healthy ferrets, I do not advocate the position publically. Its so much easier just to say, "Don't use it." Q:"I know ferrets need taurine. I also know that taurine is in meat, but what I don't know is if meat baby foods would provide enough taurine for a sick ferret. Any thoughts? A: Dirty or clean? Or involving the color red? Taurine is an amino acid where low levels have been shown to cause retinal degeneration in cats (C. D. Aguirre, 1978 J.A.V.M.A. 172:791), and may cause similar problems in ferrets. It is linked to dilated cardiomyopathy (P. Pion etal 1987 Science 237:764) at taurine levels that *prevent* retinal degeneration. Taurine has many functions; it is important in retinal mantainence, it is a neurotransmitter, and it is extremely important as a component of bile salts, used in fat absorption. In almost all animals, taurine can be synthesized, so is not an essential amino acid. In a few species, primary carnivores for the most part, taurine is *NOT* made by the body (since it is found in quantity in consumed animal bodies) and *IS* an essential amino acid. Cats have been identified as an animal where taurine is essential, but it is not listed as essential in the Fox book on ferrets (2nd ed). I ran multiple searches on Medline, Current Contents and Biological Abstracts, and could find *NO* paper supporting the idea that taurine is an essential amino acid for ferrets. Since taurine is synthesized from cystine, and both are contained in quantity in animal tissues, a diet of animal protein solves the problem, provided it is not cooked to denaturation. I have read in a few wildlife nutrition books that taurine is more important than supposed, and should included in primary carnivore diets. This is not a problem in a natural-based diet because taurine is naturally found in animal tissues. The historical problem in cats has been in the manufacturing of cat food; a process in which cooking temperatures denature the taurine, leaving a net loss of the amino acid. Dog food, historically high in plant proteins and low in overall protein content, can result in low taurine levels when fed to cats. But, while the food is unhealthy for ferrets, again, there are no published reports a dog food diet results in taurine problems. As for the taurine in baby foods, I honestly do not know if it would be a problem or not. Humans can synthesize taurine, so it wouldn't be something of concern in making the foods, and to be honest, I could find no mention of it in the literature. I know the mechanical process of making the food would not harm taurine; my only concern would be in the heating process. There is an easy way to get around the problem if it seriously concerns you; a few drops of a cat taurine supplement dripped into the duck soup wouldn't cause any harm. Probably unnecessary, but harmless. One final thought. Even though there is a remarkable lack of literature linking the need of taurine to ferrets, ferrets have some common problems that may or may not be symptomatic of low taurine levels; namely, dilated cardiomyopathy and retinal degeneration. It is possible that, even in the current absence of established needs, that a link may exist; perhaps only in a small number of ferrets possessing some recessive trait. So buying food containing taurine, or even buying a small bottle of taurine supplement and adding it to "foods for the sick" may be a help, and it certainly wouldn't hurt. If nothing else, you could be buying piece of mind, even if the addition of taurine is unnecessary. Bob C and 20 Mo' Biochemical Beasts [Posted in FML issue 2569]