Hi there! From what I know about ferrets and allergies, people who have allergies do *not* tend to be allergic to ferrets - I don;t think it's a common allergy, the way cats are for example. On the other hand, I get the impression (and this is all antecdotal evidence, not studies) that ferret alleriges tend to be rather severe when they do exist. I myself am midly-to-middling allergic to almost anything that breathes and bears fur, and I noticed a reaction to the ferrets when I got them for the first time. These symptoms did diminish as I got used to the beasties, but when I added a new one this year, I ended up in the hospital, and I have *never* been anywhere near that bad before! So yes, your sister & in-law-to-be may be allergic, even if they don;t have other alleriges, and it may be a relatively strong reaction. On the upside, if they have frequent contact with the ferrets, the symptoms may diminish, and if they don;t have frequent contact, well, all the better! I wouldn't reccommend they kiss your ferret on the lips, though...:) Megan and the allergens Anastasia ('Stop wheezing, I can't sleep.') Lexie ('I knew that new girl would be trouble.') Sammi ('I didn't *mean* to send you to the hospital, Mom, really!') -- "I do it for the joy it brings, because I'm a joyful girl." - Ani di Franco [Posted in FML issue 2435]