I can't say a whole lot on the subject,only personal experience.I don't know whether they breed for health or not,but my first sable MF female had adrenal.Not the ordinary kind,but both glands.Unfortunately,she didn't make it through the 2nd surgery.That was four years ago.Now it looks as if my second sable MF female also has adrenal disease,same age at onset.Hopefully not both glands.They were and are the sweetest ferrets you could want,and definite characters.It may just be my luck,or it could indicate a deeper problem.I really can't say as 2 are a small sample to go by.I have one more MF ferret,a male sable 2 yrs.old,so I'll keep you informed.Keep good thoughts for Jasmine and we'll get through this better. Sandy and 3 Fuzzinators Murphy had ferrets. [Posted in FML issue 2363]