In regard to your post on your MF gal-- how old is she??? It may well be if over 2 yrs of age that she is displaying symptoms of adrenal disease. Don't get me wrong we have seen this here and even at younger ages. Not sure if the MF has anything to do with it-- that is just all we have had here and all seem to have had this same condition(s) (the females that is). An already altered female ferret SHOULD NOT be displaying hormonal sypmtoms or indicators -- of being in estrus. Both the enlargement of the vulva and the enlargement of the mammories ( teats) are just that. Please confer with your veterinarian. fondly in ferrets, alicia a shelter mom [Posted in FML issue 2218]