I have been on this list for just under a year and Debbie Kemmerer's (DVM ) comment about this (FML 2196) had me curious as well. Granted, many (most?) of the ferrets sold in the US are descented before sale, but I can't recall reading about even one case of anal sac cancer (anal sac adenocarcinoma). Impacted glands, yes. Infected glands yes. Maybe I missed it, I do skim sometimes. There are plenty of folks on this list with 'scented' ferrets. Is there anyone on this list who has had a ferret diagnosed with anal sac cancer? -Ilena Ayala [Posted in FML issue 2204]