WARNING! When giving any medication watch your ferret for at least 1 hour aftewards..... Late last night I gave Gizzie his first dose of Lysodren and not 10 minutes later he had the red ferret allergic reaction. I am so thankful that Gizzie came to me (as they all do when they are sick - it really is amazing). He walked in to the room, looked at me then flat ferreted. I noticed right away his nose was pinker than usual. By the time I picked him up (30 seconds maybe) his nose, gums, and paw pads were bright red! I grabbed the Benadryl and gave him 1/2 cc, grabbed the Dex/Atarrax and sat it on the tray beside me (injectable but only if the reactions cause severe breathing difficulties - to be injected in the thigh muscle) and called the emergency vet number. I explained to Travis what happened and what I'd already done and that Gizzie was breathing o.k. Travis said to watch him closely for an hour and he should be fine. Boy did I watch him closely. The hour went very quickly (you'd think staring at and petting a ferret for an hour would seem to be a long time) and Gizzie JUMPED up and scratch, scratch, scratched. I knew he was o.k. then. He was bright eyed and even played a little. This was Gizzie's first dose of Lysodren. Rule is that they have to be exposed to something at least one other time before they can have a reaction. The Lysodren is cut with lactose - couldn't be that as Gizzie gets goats milk daily with no reaction. Perhaps the base of the Lysodren. Moral - Watch for reactions on all medications, including first doses. Hugs to all. tle [Posted in FML issue 2070]