>From: Bob Church <[log in to unmask]> >Subject: Bob C: Alive!; Selegiline Question; Adoption Hi again Bob! >I was asked about the use of Selegiline (L-deprenyl HCl/Anipryl) in ferrets >to combat adrenal tumors. I've heard of it being used in certain human >nervous system disorders, but never with ferrets or with adrenal disease. >Anyone have any knowledge or experience, including dosages? Please, anyone with experience speak up! This just came up on our Adrenal List, and we need information. One of my vets is recommending Lupron as a drug to interrupt the pituitary-adrenal-pineary feedback loop that stimulates adrenal tissue into hyperplasia and neoplasia. She's had success with it. I haven't had a chance to ask her about L-deprenyl. Also, if your male ferret is showing any signs of having urinary problems and is suspected or confirmed of adrenal problems, treat for adrenal and check into Lupron (which should help decrease the enlarged prostate). Once they block up due to prostate enlargement and ensuing urinary tract infections that create mucous and crystals, it's difficult to bring them back - catheterization is very difficult, and other problems, some fatal, can arise. Ferrets mask symtoms. Urinary infections can be checked on with a dipstick test a couple days a week (ask a vet), which I didn't know at the time. Percy blocked up and we lost him; he'd been treated for urinary tract infections, and we couldn't see any blood in his urine, (like my cat's gotten with UA infections) so we thought his treatment could wait a couple weeks. He was playful, but was dripping and urinating often. Seven months prior an adrenal exploratory showed normal adrenals, with some hyperplasia; a bit of the right was removed and his hair grew back but, obviously, his disease progressed. Mary McCarty lost Bear in June to a urinary tract blockage. But it looks like our Adrenal List's Bobo is going to make it, after a difficult struggle! They can go on dripping and urinating often for some time, but block immediately. Don't wait!!!! One of my vets used Lupron (with Lysodren) for her pet adrenal-diseased ferret and the urinary blockage (his prostate was very enlarged) completely cleared up. He was bouncy and quite furry on these drugs for three years, and she monitored him closely for his insulinoma. When he passed away a thorough necropsy showed the prostate very small and the adrenal tumor shrunken. It was a pancreatic tumor that killed him, and some signs of heart problems related to his aging (7.5 years old). For info on the Adrenal List, write me. Bob C. I hope Sandy soars through her surgery and has a successful recovery. You're a great ferret dad and Elizabeth a great ferret mom. >She is *so* very sweet, and licks the inside of my elbow for extended >periods of time, with only the gentlest ocassional chomp. Oh, I don't want to pop your romantic bubble (or any of your bubbles :), but it's come up on the adrenal list lately that adrenal fuzzies may lick skin a lot more than non-adrenal fuzzies, perhaps because of a salt craving and maybe you could figure out why?.... I'm sure Sandy loves you ardently and adamently all the same! Hugs to all fuzzies, those lost from love, and those safe in their snuggle sacks, furry, furless, black or purple, with a million toes or none... Lynn and, always, the long-bodied fur Gang [Posted in FML issue 2013]