>My question is, I know those of you that give your own distemper shots >usually pre-treat with childrens Benadryl. How much do you give (orally I >assume), and how far in advance of the distemper shot do you give it? If >the ferret does have a reaction, do you give more Benadryl, or do you either >head for the vets, or give a shot of something like Recover? I have NEVER pretreated a ferret with Benadryl or anything else before giving a distemper shot. If the shot is safe, you should not have to pre-treat. I have used about 50 FERVAC and over 1000 FROMM / GALAXY D shots. I give all my vaccinations in the rump area, and try to do shots during vet office hours, but have never needed to take a ferret in for a reaction. I have had a ferret react to a rabies vaccination given at a clinic, and she was given something and then we went home. I just have not revaccinated her since then, and she is now 8 years old and doing just fine. Pamela Troutman Grant [Posted in FML issue 1924]