In reading the posts on Roxie and the suspected insulinoma, I would just like to relay my compassion and support to Roxie's Mom and the Cheryl. While this may not be the same type of episode-- I think sharing is always a good thing when it comes to ferret health. We had an older kid who one year ago started showing the occasion wobbling signs, he was a thin kid, and on May 16th last year he had his very first full blown seizure. While the shelter Mom and Dad were doing an education event upstate, the shelter helper called and we coached her through the insulinoma diagnostics. The seizure subsided, and we put him on a insulinoma protocol. What I think is important here is to tell you the blood levels showed no signs of insulinoma, we were without explanation and over a period of time the seizures would manifest over and over-- each time being more violent and exhausting. From shortly after the first few seizures our boy developed a cataract in his left eye-- as he was over 7 we thought nothing of it. In October the ferret awoke in the Am with one eye very bulbous and greenish in color. Our regular vet not available (once again we were on an educational trip) the shelter vet used the backup ferret knowledgeable vet. He tried to claim the ferret (without any history) had an ulcerated cataract. Treated with antibiotics and asked to surgically stitch the third eye lid shut. Thank goodness the volunteer didn't bite on this but deferred until she could consult. When we returned it was evident at least to me who had been watching the seizures accelerate from mild to violent that the reason for these was a tumor. Our boy was in pain and as I held him he chittered and ticked-- (I think he was asking for rest). We took him over to the shelter vet after hours and she examined him and confirmed my already held suspicions. A retro bulbar tumor ( I think that is how she stated it). Our boy ate a raisin, gave me kisses and finally slept a peaceful sleep. The eye was removed just to make sure we weren't wrong. The eye itself was fine, no ulcerated cataract, no infection at all. The green was from the pressure of the tissue against the eye. There was a large mass of fibrous tissue where they eye cavity should be. I did not send a sample out.. perhaps now I feel it would have been worth it. There IS a possibility that there may be some lymphosarcoma or other growth causing the seizure behaviors. They could also be on the brain stem, we lost a gal to lymphosarcoma of the brain stem, she also seizured. The unfortunate part is without knowing where to look, by the time we ( ferret caretakers) find it the animal has little hope left. I send lots of love and hope for your Roxie, may you be able to isolate the cause of her physical manifestations in time to give her some more quality time. Fondly in ferrets, Alicia a shelter Mom [Posted in FML issue 1937]