My opinion is -- that if the ferret is altered you have no need of descenting. The procedure of removing an anal gland can cause more problems than not IF the vet is not thoroughly familiar with the procedure. The best advice I can think of is -- if it's not broke don't fix it-- therefore unless your ferret has a problem such as recurring infection in the anal gland leave it alone! It takes 10-30 days after neutering and the scent reduces greatly in the ferret. This is a hormone issue, not a poofing problem, so if your ferret is comfortable at home and doesn't get scared you will be just fine! Alicia a shelter Mom [Posted in FML issue 1894]