This reply is for Elayne who asked if other ferrets (female) were found to have adrenal disease without swelling of vulva. We preformed six adrenal surgeries on shelter kids last year, four of which were females, only one had a swollen vulva. The others had hair loss. The two males had balding patterns, one also had multiple cancers and was not revived. So far this year we have done or assisted families with 8 ferrets - 6 females (2 with swollen vulvas) otherwise all had the symptomatic hair loss. It is not always a swollen vulva that denoted affected adrenals, and I would caution those with balding ferrets that waiting for the vulva to swell before the surgery option may in fact give the gland more time to affect other organs. If you have a question please see a vet-- The other side to this argument is that we have seen female ferrets in beautiful show coat-- and evidencing a swollen vulva-- clearly each animal will vary in demonstrating the symptomatic signs of adrenal disease. Fondly in ferrets, Alicia a shelter Mom [Posted in FML issue 1917]