To Scott Lehman; Just thought I'd pass along, once again, my thoughts on the reaction problem you've encountered with Fervac-D: First of all, if you or your vet are administering the vaccination, check the vile's expiration date and how has it been stored. Fervac-D must be refridgerated for storage.(An expired date or improper stored vile should never be given.) Second, if you or your vet are administering the vac, when the fluid is injected into the powder, make sure all of the power is mixed throughly by rapid shaking of the vile and visually checking the bottom of the vile for stuck/caked powder. Keep shaking until it is throughly mixed.(Powder that has not throughly mixed will give an unwanted reaction. Also, a weakened vaccination is not what you want.) Third, warm the bottle by keeping a tight grip on the vile in the palm of your hand (or your vet's) until you can no longer feel a chill from the bottle.(Ferrets will have a shock reaction if a COLD vaccination is given.) Last, never, never, never give a distemper shot into the scruffed area behind the head (neck). The point of entry is too close to the brain, especially as the vac is absorbed into the body. Fervac should be given into a scruffed area around the rear leg or "hip" area. As someone who has lost and just about lost ferrets to Fervac injections, I can tell you that since we went to this procedure, we haven't had one reaction or loss. Mark Beaton B10 Ferrets, Inc. [Posted in FML issue 1860]