From Dr. Bruce William's Helicobacter faq: "The most commonly accepted treatment is a combination of amoxicillin at 10-20 mg/kg twice daily, metronidazole (Flagyl) at 30 mg/kg once daily, and Pepto-Bismol (1/15th of a tablet once daily). This "triple therapy" has been shown to be effective in man, and to a large part effective in ferrets, but must be continued for 4-6 weeks. Unfortunately,ferrets CANT STAND the taste of both Flagyl and Pepto-Bismol, and client compliance with therapy is often a problem. A recently published protocol for treating ferrets is a combination of clarythromycin (Biaxin) at 50 mg/kg once daily, and amoxicillin at 35 mg/kg once daily, or 20 mg/kg twice daily. This therapy is only continued for two weeks, and supposedly has great efficacy and causes minimal resistance in the organisms." I used the Biaxin/amoxy on my little girl Belle with good results. It is more expensive, but try to get your vet and pharmacist to give you the dry ingredients and let you mix up as much as you need. (The stuff only lasts a couple weeks after mixing with water.) My $30 bottle of Biaxin has been used to treat 3 ferrets and I still have 1/4 bottle left. A bottle of Amoxy can last a long time if mixed as needed. Linda Iroff North Coast Ferret Shelter Serving Northeast Ohio http://www.oberlin.edu/~liroff/ncfs.html [Posted in FML issue 1850]