I posted last year about my hob, Hellmutt, who had a severe reaction to Fervac-D the year before. So last year he was pretreated with steriods and Benedryl beforehand and still had a severe reaction. This year we pretreated and vaccinated with Galaxy-D and he had no reaction at all. So keep in mind, anyone who's ferret has a vaccine reaction, try a different vaccine the next time. It may not cause a reaction. Cindy DreamCatcher Ferrets [Posted in FML issue 1824]