Someone posted about a ferret who has been sick for 3 weeks, on pepto 4 times a day, etc., then watery diahrrea became present, and the ferret is losing weight, etc.. This sounds like your ferret may have a secondary infection. This can be very serious! Don't hesitate to get your ferret to a vet experienced with ferrets and these situations. Your ferret probably needs antibiotics. Didley, one of mine, suddenly began having watery diarrhea during an otherwise average case of ECE, and he went down fast! The vet put him on Metronidazole and he improved almost immediately! But he was in serious condition and may not have survived without this treatment. Please take action immediately to get your ferret to a vet. Personally, I would probably stop the pepto at this point too, sometimes if they are on it too long or on to large a dose, it can cause problems too. Email me to keep me updated on your ferrets progress, I may also be able to help with other recipes to help, etc.. I suggest you get some Deliver 2.0 and get him started on that to stabilize him as you are trying to get him back on food again. Hugs to the fuzzies Trish Director, Ferrets First Rescue & Shelter [Posted in FML issue 1726]