Two years ago, my little Zaque went through the exact same thing. From what I read, I would bet my very last dollar that it is fleas. By the time we got Zaque to the vet, they could not even get blood out of him. We gave him ferrettone and ferretvite. We used a dropper to feed him kitten milk, and force fed him soft food that the vet gave us (Sorry, I can't remember the name). After all that, he still did not get better. So off to the vet we went again. This time he gave me an antibiotic for Zaque, he thought an infection had set in. This worked! (along with a continuence of the feeding process). Another thing is Program is a wonderful product, but it does not prevent the fleas from biting Weezie and ferrets have so little blood to give. We have found a waterbased flea product by 3M that is our godsend in our little zoo. It is very powerful and is harmless to your fuzzie (or kittens for that matter). Make sure Weezie is getting lots of nutrients, lots of TLC, and get rid of the rest of those nasty fleas! My heart goes out to you. Good luck and please keep us posted, if not on FML, then e-mail us directly. Sular, Zaque, Symon, Kara, Gershwin, and Chester [Posted in FML issue 1707]