I think this is a case for an adrenal tumor most likely, Lost of hair on the tail, lathargic and swollen vulva. It does sound like a adrenal problem. If your vet does not know much about ferrets I suggest going to a new one. Have you read the medical faq's yet on an adrenal tumor or insulinoma? If not go to my web page and follow the link. Peace is through Superoir Fire Power... Home of the happy ferret's Salen and Josey.... And a very sick one (healing slowly) with a new name Lois I can be reached by E-Mail at [log in to unmask] or phone (215) 743-1774 Please note when contacting me by voice you ask to speak to Al Smith of KwikSilver Computer Services. KwikSilver Computer Services Albert Smith-Owner http://www.voicenet.com/~asmith/main.html [Posted in FML issue 1706]