To Becki Kain - >The problem is that he is naucous all the time, wimpers, and is not eating >on his own. He is often in a dazed state, pulling at his mouth with his >hands, and drooling. Becky - the drooling and dazed state is probably due to the insulinoma. However, the nausea may well be the result of the chronic kidney disease. You're definitely in a bit of the bind. Prednisone which is used to raise blood glucose in insulinoma patients increases wear and tear on the failing kidneys. If the kidneys are really shot, then you can't do the surgery, and have to administer the pred. I'm not sure about the Winstrol to treat renal failure - is Tieke anemic? Certainly, they are not acting as appetite stimulants, as they are often prescribed. They may further decrease the blood glucose due to their anabolic (muscle-building) process. If they aren't adding to the treatment, I would start by removing them for the regimen. My first thought would be surgery if Tieke is a surgical risk to try and remove the insulinoma. It may buy some extra time..... Bruce Williams, DVM, DACVP Chief Pathologist, AccuPath [Posted in FML issue 1664]