Dear Vets, Now I know that if we were to premedicate a ferret before vaccines we would use Diphenhydramine. I understand this is an antihistime which would block the allergic reaction that causes the histimines to bombard the body. But if we were to wait for a reaction would we use Epinephrine,and what dosage,to stop the closure of the blood vessels and than administer Diphenhydramine and if so in what dosage? My ferrets have never had any reaction to any vaccines but since I live in a FFZ and the vets are not as knowledgeable as those on this list I would like to present this information to my vet so that he might be able to assist any reaction that might occur. Since I do live in a FFZ could you please post any responses to this list and if any added information is required I can than respond to you e-mail. Thank you for your time. Christine [Posted in FML issue 1640]