Melissa-- I strongly second what Vicki said-- I have asthma too, and I react much more strongly to cats than to my ferrets. If they haven't had a bath in a while and one curls up on my pillow at night, I have some problems (more so with the male, perhaps because he's not descented) but otherwise life is normal with them. I do bathe them more frequently than most people on this list seem to bathe theirs (once a week; no skin problems, and lovely plush fur), so that might help. Also I found that I react to clay litters, because of all the dust. Switching to pine pellets or newspaper pellets, if you use clay, can help the general air quality of your living space, not to mention using an air purifier. Good luck in sorting out your allergies, but don't give up on the ferrets right away (although I assume that giving up the cats wouldn't be any easier :-( ) Regina [Posted in FML issue 1552]