I have a 5 1/2 year old descented and nuetered male ferret that is exhibiting hair loss in a pattern I believe symptomatic of adrenal insuloma. The vet took a urine sample today for a cortisol/creatinine (I think) ratio and I'll know pretty much for sure in a few days. I recall past discussions about treatment and am willing to consider surgery if necessary but I'd like to find out more about Metadine (sp?). This has been used on dogs I believe to shrink adrenal tissue and tumors and I think some discussion on it here happened also. My vet knows of the medication but has little or no experience using it with ferrets. Could someone point me to past issues of the list that might have any information. Also I would welcome comments from anyone with experience using the drug on ferrets. Any info on dosages, contra-indications, side-effects and efficacy would be welcomed. Many thanks in advance! Steve [Posted in FML issue 1513]