Unless you have some other explanation for the initial high protein reading in the urine, you might want to go ahead and do the renal panel. Kidney problems can cause weakness in the back legs -- that happened to one of my beloved fuzzies who later died of glomerulonephritis (a kidney disease). The sooner you catch kidney problems, the sooner you can begin treating them. Now, please ignore this suggestion if one of the vets here has another explanation for the high protein reading. Linda [Posted in FML issue 1449]