Brian asked "...I was wondering if anyone has noticed intro's going smoother when the ferrets are of the opposite sex." I had only Slinky (3 year old Sable female) at first, then decided to get her a partner (Bandit -- 1 year old Sable male). They got along quite well from the start. Bandit was almost as big as Slinky even when we first got him ... now he is quite a bit bigger than she is! Four months later I got Rascal (10 month old Silver female). She was no bigger than the palm of my hand when I got her and was still eating canned kitten food and learning about the litter box! I took longer introducing Rascal to the other two out of concern for her size (or lack thereof) and frailty compared to the ofttimes brutish Bandit (he means well but he doesn't realize how big and strong he is!). From the start Bandit and Rascal played the most together ... and the hardest. They are now best buds ... with Slinky coming into the picture whenever she feels the urge (can we say matriarch!). It took Slinky a lot longer to get used to Rascal ... Rascal was a ball of energy to start with and putting her next to Bandit made her much worse! Over the past few months I have noticed Slinky acting much more energetic when she plays and she is dooking and war dancing up a storm!!!! Maybe Rascal is rubbing off on her! So Brian, no, I haven't seen any inter-sex problems with introducing new ferrets. I think the more important factor is getting a ferret with a similar or compatible personality to NIXON's. If the new ferret is drastically different (i.e., like Slinky and Rascal), you should take the introduction much more slowly. This is only my opinion as a ferret owner who has already gone through two introductions. I'm sure many others have equally good advice (and probably different) to give from personal experiences. Good luck, Brian! Marc Wilson, Slinky, Bandit and Rascal [Posted in FML issue 1412]