To Tetsura Oka: >There is one approved distemper vaccine in US. But no approved vaccine in >Japan. I want to ask veterinarians here. If you were in Japan,which do >you use Fervac-D or Fromm-D(Galaxy-D). Of course both ware not approved in >Japan. Well, you've certainly got it straight. I think if I was dealing with ferrets in a country where neither was approved, I would probably go with Fromm-D, because there are less reactions (but remember, you may still see some.) That would answer the "safer" part of your question. As far as effective - we have no knowledge of Fromm-D effectiveness in protecting ferrets from distemper. Fervac-D has been tested in ferrets and approved by the USDA. Currently, I have some questions in my mind about Fervac's actual effectiveness, but certainly it has the better track record. Bruce Williams, DVM, DACVP [Posted in FML issue 1391]