Ferret shots: new kit - distemper at 8 weeks, 11-12 weeks, 14-15 weeks (i.e. booster at every 3-4 week interval). If purchased at the pet shop, ask the arrival date the kit came in and give the second booster 3 weeks after that date. Rabies can be administered as early as 12 weeks, but keep this shot separate from the distemper by 1 or 2 weeks. No booster is needed. new adult - no know shot record? vaccinate against distemper and then boost 3-4 weeks later. Rabies can be administered as any time, but keep this shot separate from the distemper by 1 or 2 weeks. If you know the ferret was inoculated within the last year, then only one shot is needed to keep them current. If you want to move a new ferret to your present ferret(s) schedule, or visa versa, then as long as it has been a month since the previous shot, go ahead and re-vaccinate. Annual boosters are required for distemper and rabies. Keep these shots separate by 1-2 weeks and in case of reactions, wait at the vets for at least 20 minutes after the shot is given. Recommended vaccines are Galaxy-D and Fervac-D for distemper. Imrab 3 is the ONLY approved rabies vaccine for ferrets at this time. Pam Grant / Shelters That Adopt & Rescue Ferrets [Posted in FML issue 1360]