Drs. Williams/Weiss: Is anything known whether reactions are to the vaccine or to a preservative or some other agent in the mix? (Yes, the following reaction is being reported to the manufacturer and to the FDA.) Well, we've had two out of three so far this year. Yesterday our 18 month old had a reaction to Imrab. Same as with our oldest ferret earlier in the year. After about five minutes she started to flush red and crawled into her carrier and hid. (Note this and the previous occasion both ferrets reacted to Imrab. We've had no problems yet with Fervac.) According to our vetinarian, last time when she called the manufacturer (Rhone Meriuex - not sure of the spelling.) they insisted that they had no reports of reactions to the vaccine. So far she is still sleeping it off. She's eating and drinking well but is _VERY_ lethargic compared to normal and the rear end is in a state of hopefully only temporary paralysis where she had to be injected to counteract the reaction. [Posted in FML issue 1322]