To Nina Janes: >My vet no longer uses Fervac-D (he's had too many reactions he says), but >instead uses Vanguard by Smith Beecham Kline. Then you are not using a ferret-approved vaccine. Recently, I saw a case of a "distemper-like" syndrome following usage of an unapproved vaccine which is primarily used in dogs. While I have tended to be more accepting in the past with extra-label usage of distemper vaccines, I can no longer justify the use of just any vaccine off the shelf in ferrets. Fervac-D, in my opinion, is still the "gold standard"; Galaxy-D is usable in cases where animals have previously reacted to Fervac. By using any other vaccine, you are at risk. Bruce Williams, DVM, DACVP Dept. of Vet Path, AFIP [log in to unmask] OR Chief Pathologist, AccuPath [log in to unmask] [Posted in FML issue 1311]