To Pat Patterson: >Luferon is not listed for ferrets, but I recall Dr. Williams saying he >used it. It says to give on a full meal. Actually, I said that it should pose no harm for ferrets and that a lot of people are using it, but I am not one of them. Our flea problem is such that we have not had to resort to extra-label usage of this drug on the ferrets. We DO use it on the dogs, however. The literature does not say why it needs to be given on a full stomach. The two most plausible reason sis that a) - it is mildly irritating to the stomach lining, or b) the drug is fat soluble, and the presence of fatin the stomach gives it a higher rate of absorption. Bruce Williams, DVM, DACVP Dept. of Vet Path, AFIP [log in to unmask] OR Chief Pathologist, AccuPath [log in to unmask] [Posted in FML issue 1285]