To Mark Brgr: >I have a 2 year old spayed female, a bit over two pounds, who has developed >a swollen vulva (size of medium pea) over the last three weeks. No other >noticeable changes. My vet... advises to wait two months, then do an ultrasound to assess I hear a lot about the wait and see approach. However, swollen vulvas in a spayed female are a definite sign of disease, usually adrenal. While 2 years is under the average, it certainly would not be unusual to see adrenal disease in an animal of this age. I'm not a fan of waiting and seeing. This is not a case of marginal hair loss but a definite sign of disease. All that waiting can do is make an adrenal disease larger (which can be a real problem if it turns out to be a malignant tumor). Probably a far better idea to explore the abdomen now.... Bruce Williams, DVM, DACVP Dept. of Vet Path, AFIP [log in to unmask] OR Chief Pathologist, AccuPath [log in to unmask] [Posted in FML issue 1295]