Meg, Welcome to the FML! I hope you have as much fun with it as I have had. Your posts have had me in stitches - I know how you feel about computers - I'm hooked into the Internet from my word processor at work - about all I know how to do is send mail and I recently learned how to forward messages!! A major accomplishment!! Frankly, Meg, I agree with you. I can't help but believe that taking out sex glands at such a young age can be anything but detrimental. I worked in a human genetics clinic for 6 years, and we were constantly seeing developmentally delayed children as well as growth retarded children - some of who had hormonal deficits. It seems to me - in my opinion - that since ferrets and humans are both mammals - is it not possible that these 2 mammalian systems could react in the same way to hormone deficits? Well, maybe not in the SAME way but similar ways? I'm not saying that humans develop adrenal tumors, I'm just saying that a lack of these hormones during development just may account for other systemic problems. As more and more ferrets are purchased from breeders and most likely are being neutered at a more normal (IMO) age of around 6 months, it will interesting in a few years to see if these ferrets will end up developing adrenal tumors as well. BTW, Judi Bell gave me a study that was done by Mary VanDame - I think - Results of the report indicate that early neutering does not cause an increase in adrenal tumors - I'll have to go dig it out from somewhere on the dining room table - that may take a couple of days :) and I'll post the specifics. But like I said, my gut feeling tells me it *has* to make a difference. Debbie Riccio WNYFLFA Rochester, NY [Posted in FML issue 1219]