Once again, I would like to thank everyone who has posted privately to me, including Debbie and Gary. I understand where you were coming from now, and want to apologize myself for taking offense at a trivial misunderstanding. All of the private postings brought me tears of joy, as all of you really now how to put things very eloquently! To Dr. Williams, I have a 3 1/2 year old female Marshall Farms ferret (Zola) who had an adrenal tumor taken out last year after she began losing weight and hair, and her vulva was swollen. Now, a year later, she's losing weight again and her vulva is swollen. I knew immediately that her second one was acting up, and my vet agrees. A classmate suggested using Lysodren to specifically kill the adrenal cortex, and to use it as a titration to effect. My vet is curious whether we can remove the second one and supplement her on Prednisolone for the rest of her life. I prefer not to put her throught this risky surgery if I can target the adrenal with Lysodren. What is your experience with both of these options? Thanks for your time! Carie Guppy, Virginia-Maryland Regional College of Veterinary Medicine, Class of 1997 ( and her Zoo) [Posted in FML issue 1191]