Spiney Norman, There are several diseases that can cause a ferret to drink and urinate more then normal.These include diabetes, kidney infection, kidney failure, liver disease/failure, kidney or liver cancer. Since there are so many potential causes and some are serious it is important to do some lab tests rather then the "shot gun "approach. It would also help to know how old she is (in older ferrets we are more concerned about kidney failure or cancer). I would strongly recommend bloodwork and a urinalysis at the least to help diagnose and therefore properly treat your companion. With diabetes there is glucose in the urine and the blood glucose is greater then 160. This is treatable with insulin shots. There are also oral medications for diabetes; unfortunatele they are ineffective to treat dogs with diabetes and there have not been studies in ferrets (to the best of my knowledge). Good Luck Dr Weiss 301-299-4142 [log in to unmask] [Posted in FML issue 1148]