Hi guys! Glad to hear Daphne is gaining weight and doing well, she is lucky she has such a nice home now. I quess she is feeling strong enough for her distemper shot, I am sure she is thrilled. As for Coffee having a lump after the vaccination, that is common with the rabies vaccinations, we see it also in dogs and cats. They are commonly just sterile abcesses and will go away with time and the care Dr. Bock told you of, but it is good to always contact the vet. I do not think there is away to prevent them. In dogs and cats certain brands of rabies cause it, but for ferrets Imrab is the only safe rabies vaccination, so you can not switch brands. Rick said you had called and I am glad you called Dr. Bock about it also. Just be sure a veterinarian always gives the rabies incase of a more severe reaction. Take care and see you soon. Stephanie [Posted in FML issue 1146]