To Deborah Riccio: Deborah - I talked with Dr. Balonek todya about this ferret. My suggestion is to take a look in the abdomen to see if we can find a pancreatic neoplasm and also take one of those big inguinal nodes. I do advocate surgery over medicine every day, but you also have to throw the animal's age, debilitation, and sometimes other factors such as economics into the equation. I do know that no practitioners are really thrilled with proglycem for insulinoma, and it gets very expensive very quickly. It' still your decision - if it was my ferret, and I trusted Dr. Balonek's skill, I'd go for the surgery. Bruce Williams, DVM Department of Veterinary Pathology [log in to unmask] Armed Forces Institute of Pathology (202) 782-2600/2602 Washington, D.C. 20306-6000 [Posted in FML issue 1150]