Tammy - here is a copy of the report on your ferrets adrenal tumor, which I have sent to Dr. Weiss. Sorry - I've lost your email address. VETERINARY CASE WORKSHEET Accession number: 2483345 Date:February 26, 1995 ______________________________________________________________________________ MICROSCOPIC DIAGNOSES: S-000-95 Adrenal gland, cortex, right: Carcinoma, adrenocortical, ferret, mustelid. COMMENT: Adrenocortical carcinomas are common neoplasms of the ferret adrenal gland, and may result in various cutaneous, repoductive, and behavioral abnormalities due to release of excessive estrogens (adrenal-associated endocrinopathy). In our experience, while these neoplasms may attain a large size, metastasis to other visceral organs is rare. The following references may be of interest to you: Lawrence HJ et al. Unilateral adrenalectomy as a treatment for adrenocortical tumors in ferrets: Five cases (1990-1992). JAVMA 203(2): pp 267-270, 15 July 1993. Lipman, NS et al. Estradiol-17 -secreting adrenocortical tumor in a ferret. JAVMA 203(11): pp 1552-1555, 1 December 1993. Hope everything clears up. Best of luck. Bruce Williams [Posted in FML issue 1119]