To Ed Hughes - Sorry to be so long in replying, the usual network problem. Ed, your vet doesn't know too much about ferrets (I'm trying to be diplomatic here." Yes, the signs that Mei-Mei is showing are very suggestive of adrenal disease, and I strongly urge the exploratory surgery. However, if your vet is using "Cheque", he/she is way out of the bounds of good ferret medicine. Adrenal tumors are fairly easy to remove, if you know what you are dealing with. My suggestion for you is to either have your vet give me a call, give me a call yourself, (if you want to continue with this vet), or download the STAR database and see if there are other vets in your area that are more familiar with ferret disease. Stop the Cheque drops, also. Cheque is a progesterone analog that was used as birth control for dogs for a while, but I don't even think that it is used in dogs any more. Lord knows what it will do in a ferret.... Bruce Williams (202) 782-2600 [log in to unmask] [Posted in FML issue 1091]