Recently, an inquiry was made about the treatment of ear mites with ivermectin. At that time, I said that I believed that ivermectin was only given orally or subcutaneously to ferrets with severe infestations, but not topically (rioght into the ear). Today I ran across an article (Bell, JA. Parasites of Domesticated Pet Ferrets. Comp. Clin. Educ. Pract. Vet. 16(5): 617-620, which gives a dosage for topical administration of ivermectin: Injectable ivermectin is mixed with propylene glycol at a ration of approximately 1:20 - then 0.2 to 0.3 ml (4-6 drops) into each ear canal daily. Ferrets on ivermectin for heartworm prevention should not have problems with ear mites. Live and learn.... Bruce Williams, DVM Department of Veterinary Pathology [log in to unmask] Armed Forces Institute of Pathology (202) 576-2453/2454 Washington, D.C. 20306-6000 [Posted in FML issue 0944]