Amy Me Cada wrote: >To all: >With the O.K. of my vet, I have been dosing my ferrets and dogs with ivermectin >for the past two years. I purchase the sterile 50 ml 1% solution at a general >feeds store and dilute a quantity each month. Does anyone have any idea if >diluted (with propylene glycol) ivermectin has a different shelf life than >undiluted, given light-free storage? >In addition to being convenient, this method is VERY cheap--about .15 a month >for all. Just MAKE SURE that you are very careful about >diluting and dosing for your animals. I do it because I work in a laboratory >and have access to syringes and other instruments for precise measurement. One >millileter of undiluted 1% ivermectin contains 10,000 micrograms! >I dilute 1:99 with propylene glycol. Any thoughts? >Amy Amy, as I'm not a pharmacologist - I'm not sure of the shelf-life of your diluted variety. A note to everyone however - Amy's method works for her as she is sure of her dilutions. I would not advise anyone not familiar with these techniques to try it, even if it is very inexpensive. A mistake by one power of 10 (or one decimal place) may prove disastrous. Let your vet make up the solution for you... Bruce Williams, DVM Department of Veterinary Pathology [log in to unmask] Armed Forces Institute of Pathology (202) 576-2453/2454 Washington, D.C. 20306-6000 [Posted in FML issue 0862]