http://www.ncbi.nlm.nih.gov/pubmed/24962052 QUOTE J Small Anim Pract. 2014 Jun 24. doi: 10.1111/jsap.12243. [Epub ahead of print] Prepuce and partial penile amputation for treatment of preputial gland neoplasia in twoferrets. van Zeeland YR, Lennox A, Quinton JF, Schoemaker NJ. Author information van Zeeland YR Division of Zoological Medicine, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584, CM, Utrecht, The Netherlands. Abstract Preputial tumours in ferrets are frequently malignant and therefore warrant prompt investigation. As many cases do not respond favourably to surgery, even in combination with radiation therapy, wide surgical resection has been recommended. Such a procedure may necessitate partial or total penile resection but outcomes have thus far not been well described. The current case series describes two ferrets in which surgical resection, including penile amputation, was performed using 10 and 5 mm margins, respectively. In the first case, no recurrence of preputial gland adenocarcinoma was noted for 32 months postsurgery, whereas multiple attempts at surgery and radiation therapy were unsuccessful in the second. These cases suggest that margins of at least 1 cm may help achieve a better outcome. Penile amputation for the treatment of preputial tumours appears to be well tolerated by ferrets, as demonstrated by these cases. (C) 2014 British Small Animal Veterinary Association. PMID: 24962052 [PubMed - as supplied by publisher] END QUOTE [Posted in FML 8138]