Notice that the way that the electroacupuncture reduced sepsis was by a major nerve stimulating the Vagus Nerve, which acted in a way not previously known. It stimulated increases in certain adrenal products like dopamine and norepinephrine. http://www.nih.gov/researchmatters/march2014/03102014sepsis.htm QUOTES Further experiments showed that stimulation of the vagus nerve triggered the adrenal glands to release catecholamines, including dopamine and norepinephrine. The electroacupuncture activated an enzyme involved in the production of dopamine in the adrenal glands. Dopamine, in turn, inhibited production of inflammatory chemicals. ... The team found that electroacupuncture wasn't effective in treating mice whose adrenal glands were removed. Unfortunately, many patients with sepsis have problems with their adrenal glands, so electroacupuncture likely wouldn't help them. To address this issue, the team focused in on dopamine. Dopamine has broad effects, activating many receptors, so they tested compounds that target specific receptors. Fenoldopam, which specifically activates dopaminergic receptor type 1, controlled inflammation and improved survival in experimental mouse models of adrenal insufficiency. END QUOTES Cushings is not what ferrets get but each piece of adrenal info adds to the knowledge base: http://www.nih.gov/researchmatters/march2014/03102014cushing.htm [Posted in FML 8063]