We have been using it since well since we couldn't get the Galaxie D years ago. I would guess we have vaccinated over 300 ferrets by now. And right now we are going through the test. One of our adoptors of 4 just adopted a puppy. The puppy has been diagnosed with distemper. By the time it was discovered, it would do no good to remove the ferrets. It is being treated. It has been 2 weeks and so far so good, no ferrets have come down with it. Yes, of course, I am on pins and needles because that was the whole thing with the vaccine that it hadn't been tested enough. In a month, I will make a report. Of course, this is no science test as they do but it will build my confidence more in using the vaccine. Millie Sanders at Txferretrescue.org with Texas Ferret Lovers Rescue and connecting Foster homes and sanctuaries [Posted in FML 8030]