Mike, I have seen maybe a handful of chylous ascites cases, and always involving lymphoma. Was cytology run on the substance to confirm if it was chyle or pseudochyle? I have seen one case where pseudochyle was present and the ferret was found to have mycobacterium infection on necropsy. You might also consider cardiomyopathy and heartworm in your differentials. I'm not sure how lymphoma/neoplasia was ruled out, but you might consider posting your bloodwork/lab results to FHL for further discussion as well. In any event, I would consider frequent monitoring for organ dysfunction since routine drainage of true chyle fluid could result in electrolyte and volume insufficiency, among other things. Regards, Bonnie Tormohlen/Vet Tech Managing Director Northern Arizona Ferret Alliance & Rescue, Inc [Posted in FML 7854]