I learned after had give our 7 year old ferret both Melatonin and Deslorin implants on the same day, that it wasn't a good idea because of the lethargy it caused. I had never heard the two together could cause this and I found out too late. How long does the lethargy last? Willy seemed a bit over tired for the first couple days then he seemed to improve, but never got really active (not that he was very active before). He has both Adrenal and Insulinoma, and a nerve problem in his lower back from an old injury. His last glucose was 106 which was on the day he got both implants. Its been about 3 weeks and the last several days he has not looked good at all. He did feel very warm and we thought maybe he had an infection or something. He has been on clavamox for 4 days and has improved some but still doesn't look good. Also his lymph nodes are swollen and we were thinking this was due to the pred, he has been on for the last couple years. We will be taking him to the vet tomorrow despite the snow storm we're hitting us tonight. We were hoping the clavamox would take care of the problem but it doesn't look like it. Can this be the effect of both Deslorin and Melatonin being given together? My next thought is some infection that the Clavamox is not doing much for. After that it could be Lymphoma (this is my worst fear). My main question is can it be the two implants causing this after 3 weeks? Thanks Mike [Posted in FML 7715]