I use the deslorelin implants and do see hair regrowth with them, without using the melatonin implants. Squirt regrew her coat soon after her des implant, then again a month after losing it after the deslorelin was depleted. Thor grew a nice coat 2 weeks after his des implant, then started thinning a month later. I've had some ferrets die near or soon after the deslorelin was depleted, some had severe prostate issues. Simba still had a beautiful coat, had prostate problems, then lost much of his fur in two weeks before he died. The time it takes to work differs from ferret to ferret from my experience. I've seen it start relieving symptoms as soon as 2 weeks and as late as 2 months and variable duration as well. While deslorelin is less costly than surgery, it is not a cure-all for adrenal disease and ferrets will have varying results. tle www.ferretfamilyservices.org [Posted in FML 7712]