Nell, the Lupron has likely worn off. The most commonly used form of the depot is the one month version but there is another that sometimes lasts as long as three months. The return to an active interest in enjoying life is seen even more often with Suprelorin which is the deslorelin implant and is a related med in the same class as Lupron but often more effective and often a more economical purchase since it lasts longer. [Posted in FML 7612]