I have had two ferrets with chordomas at the end of their tails and both were removed. If you don't remove it, it will continue to grow. Removal is an easy procedure, especially if done while it's still small. The end section of the tail must be removed, and hopefully you will have an experienced ferret surgeon, because they must also be aware that some extra âÂÂpadding' must be left over the bone at the point of removal. This is because when the skin heals, it will tighten, and without that extra padding, then the bone will be pressing against the skin, making it more susceptible to possibly breaking thru. I have not had this problem with either ferret who had the operation done and both recovered quickly and completely, and were MUCH happier without a growing tumor on the end of their tail. Here is a link with some information. Scroll down to pages 36-41: <http://www.ferrethealth.msu.edu/Diseases/Urogenital_Skin_SpecialSenses_Muskuloskeletal.pdf> And you can also search the Ferret Health List Archives for postings from vets and ferret owners about chordomas: http://ferrethealth.org/archive/ Jeff In Loving Memory of Neo, Trinity, Morphy, Dozer, Possum, Pip, Pop, Sabrina, Minnie Mouse, Hunny, Misty, Frodo, Baggins, and Mr. Parker Caring for Luna, Baby Girl, Boomer, and Zoomer [Posted in FML 7315]